Production of cyclophosphamide metabolites by primary hepatocyte cultures from male and pregnant rats: Effect of Aroclor 1254 pretreatment

Author:

Vanaerts L.A.G.J.M.,Peereboom-Stegeman J.H.J.Copius,Noordhoek J.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference29 articles.

1. Primary hepatocyte culture as an activating system for xenobiotica tested in the rat whole embryo in vitro;Bechter,1989

2. Transplacental transfer of polychlorinated biphenyls induces simultaneously the expression of P450 isoenzymes and the protooncogenes c-Ha-ras and c-raf;Borlakoglu;Biochemcial Pharmacology,1993

3. Oxidative metabolism of cyclophosphamide: identification of hepatic monooxygenase catalysts of drug activation;Clarke;Cancer Research,1989

4. Hepatic cytosolic glutathione S-transferase activities in ageing Brown Norway rats—importance of sex differences and phenobarbital treatment for studies of ageing;Coecke;Mechanisms of Ageing and Development,1990

5. Studies on the selective action of cyclophosphamide (NSC-26271): inactivation of the hydroxylated metabolite by tissue-soluble enzymes;Cox;Cancer Treatment Reports,1975

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