Directed carbonylative (3+1+2) cycloadditions of amino-substituted cyclopropanes and alkynes: reaction development and increased efficiencies using a cationic rhodium system

Author:

Shaw Megan H.,Whittingham William G.,Bower John F.

Funder

EPSRC

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference58 articles.

1. There is a pressing demand for the development of efficient methodologies that target low molecular weight (200–350 Da), 3D (sp3-rich) scaffolds:

2. Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

3. Lead-Oriented Synthesis: A New Opportunity for Synthetic Chemistry

4. Directing Group Enhanced Carbonylative Ring Expansions of Amino-Substituted Cyclopropanes: Rhodium-Catalyzed Multicomponent Synthesis of N-Heterobicyclic Enones

5. Selected carbonylative (3+1+2) cycloadditions of cyclopropanes and related ring systems, see:

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