Betulinic acid attenuates cyclophosphamide-induced intestinal mucosa injury by inhibiting the NF-κB/MAPK signalling pathways and activating the Nrf2 signalling pathway

Author:

Ou Zhaoping,Zhu Lijuan,Huang Chenglong,Ma Chaoyang,Kong Li,Lin Xing,Gao Xinyu,Huang Lin,Wen Lixin,Liang Zengenni,Yuan Zhihang,Wu Jing,Yi Jine

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Pollution,General Medicine

Reference56 articles.

1. Naringin prevents cyclophosphamide-induced hepatotoxicity in rats by attenuating oxidative stress, fibrosis, and inflammation;Adio;Food Chem. Toxicol. Int. J. Publ. Br. Ind. Biol. Res. Assoc.,2021

2. Olea europaea leaf extract up-regulates Nrf2/ARE/HO-1 signaling and attenuates cyclophosphamide induced oxidative stress, inflammation and apoptosis in rat kidney;ALHaithloul;Biomed. Pharmacother.,2019

3. Protective effects of boron on cyclophosphamide-induced bladder damage and oxidative stress in rats;Ayhanci;Biol. Trace Elem. Res.,2019

4. Betulinic acid attenuates lipopolysaccharide induced vascular hyporeactivity in the rat aorta by modulating Nrf2 antioxidative function;Bai;Inflammopharmacology,2019

5. The intestinal barrier in multiple sclerosis: implications for pathophysiology and therapeutics;Camara-Lemarroy;Brain,2018

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