G-protein inhibition profile of the reported Gq/11 inhibitor UBO-QIC
Author:
Funder
Magnus Ehrnrooth Foundation
Liv & Hälsa Foundation
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
Reference24 articles.
1. Regulation of receptor-coupling to (multiple) G-proteins. A challenge for basic research and drug discovery;Kukkonen;Recept. Channels,2004
2. A novel Gαq/11-selective inhibitor;Takasaki;J. Biol. Chem.,2004
3. Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule;Nishimura;Proc. Natl. Acad. Sci. U. S. A.,2010
4. Structure of FR900359, a cyclic depsipeptide from Ardisia crenata sims;Fujioka;J. Org. Chem.,1988
5. YM-254890 analogues, novel cyclic depsipeptides with Gαq/11 inhibitory activity from Chromobacterium sp. QS3666;Taniguchi;Bioorg. Med. Chem.,2004
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2. Recommended Tool Compounds: Application of YM-254890 and FR900359 to Interrogate Gαq/11-Mediated Signaling Pathways;ACS Pharmacology & Translational Science;2023-11-10
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