Polyamines stabilize left-handed Z-DNA: Using X-ray crystallographic analysis, we have found a new type of polyamine (PA) that stabilizes left-handed Z-DNA

Author:

Ohishi Hirofumi,Odoko Mamiko,Grzeskowiak Kazimierz,Hiyama Yoichi,Tsukamoto Koji,Maezaki Naoyoshi,Ishida Toshimasa,Tanaka Tetsuaki,Okabe Nobuo,Fukuyama Keiichi,Zhou Da-Yang,Nakatani Kazuhiko

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference24 articles.

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2. Structure of a B-DNA dodecamer III geometry of hydration;Drew;J. Mol. Biol.,1981

3. Molecular structure of a left-handed double helical DNA fragment at atomic resolution;Wang;Nature,1979

4. Polyamine-induced Z-DNA conformation in plasmids containing (dA-dC)n(dG-dT) inserts and increased binding of lupus autoantibodies to the Z-DNA form of plasmids;Thomas;Biochem. J.,1994

5. The ability of polyamine analogues to induce Z-DNA structure in synthetic polynucleotides in vitro inversely correlates with their effect on cytotoxicity of cis-diaminedichloroplatinum(II) (CDDP) in human brain tumor cell lines;Hiraks;Anticancer Res.,1996

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