Fundus autofluorescence (FAF) non-invasively identifies chorioretinal toxicity in a rat model of retinal pigment epithelium (RPE) damage

Author:

Baek David Sung Hyeon,Liang Huiyuan,Zhao Xu,Pankova Natalie,Wang Hai,Boyd Shelley

Funder

Natural Science and Engineering Council (NSERC)

2020 Network for the Development of Ophthalmic Biomaterials

Translatum Medicus Inc., Canada

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference28 articles.

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2. Age-related changes in the morphology, absorption and fluorescence of melanosomes and lipofuscin granules of the retinal pigment epithelium;Boulton;Vision Research,1990

3. A high-throughput biophotonics instrument to screen for novel ocular photosensitizing therapeutic agents;Butler;Investigative Ophthalmology & Visual Science,2010

4. Optimization of in vivo confocal autofluorescence imaging of the ocular fundus in mice and its application to models of human retinal degeneration;Charbel Issa;Investigative Ophthalmology & Visual Science,2012

5. In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics;Delori;Investigative Ophthalmology & Visual Science,1995

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