Interferences of the autonomic nervous system with drug induced QT prolongation: A point to consider in non-clinical safety studies
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Toxicology
Reference40 articles.
1. A method for QT correction based on beat-to-beat analysis of the QT/RR interval relationship in conscious telemetred beagle dogs;Batey;Journal of Pharmacological Toxicological Methods,2002
2. An analysis of time relation of electrocardiograms;Bazett;Heart,1920
3. Interactions of the cardiac chronotropic effects of rilmenidine with the autonomic nervous system;Boucher;Journal of Autonomic Pharmacology,1996
4. Calculation of QT shift in non clinical safety pharmacology studies;Champeroux;Journal of Pharmacological Toxicological Methods,2009
5. Prediction of the risk of Torsade de Pointes using the model of isolated canine Purkinje fibres;Champeroux;British Journal of Pharmacology,2005
Cited by 14 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Status of Safety Pharmacology and Present Guidelines;Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays;2024
2. Simultaneous assessment of central nervous and respiratory systems using jacketed telemetry in socially-housed rats: Application of the “3Rs” principles in core battery safety pharmacology studies;Journal of Pharmacological and Toxicological Methods;2023-05
3. Contribution of haemodynamic side effects and associated autonomic reflexes to ventricular arrhythmias triggering by torsadogenic hERG blocking drugs;British Journal of Pharmacology;2022-07-13
4. Nonclinical cardiovascular safety assessment of thioridazine: Impact of autonomic tone, body temperature, and choice of species;Journal of Pharmacological and Toxicological Methods;2022-05
5. In Vivo Methods in Cardiovascular Safety Pharmacology;Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays;2022
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3