Comparison of guinea-pig ventricular myocytes and dog Purkinje fibres for in vitro assessment of drug-induced delayed repolarization

Author:

Terrar Derek A.,Wilson C.M.,Graham S.G.,Bryant S.M.,Heath B.M.

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference43 articles.

1. Sparfloxacin but not levofloxacin or ofloxacin prolongs cardiac repolarization in rabbit Purkinje fibers;Adamantidis;Fundamental & Clinical Pharmacology,1998

2. Cisapride and Torsade de Pointes;Ahmad;Lancet,1995

3. ICHS7B: Safety Pharmacology for assessing the potential for delayed ventricular repolarisation (QT interval prolongation) by human pharmaceuticals;Anon,2005

4. Electrophysiologic and voltage clamp analysis of the effects of sotalol on isolated cardiac muscle and Purkinje fibers;Carmeliet;Journal of Pharmacology And Experimental Therapeutic,1985

5. Preclinical in vitro cardiac electrophysiology. A method of predicting arrhythmogenic potential of antihistamines in humans?;Cavero;Drug Safety,1999

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