The spectrum of “off” in Parkinson's disease: What have we learned over 40 years?

Author:

Chou Kelvin L.ORCID,Stacy Mark,Simuni Tanya,Miyasaki Janis,Oertel Wolfgang H.,Sethi Kapil,Fernandez Hubert H.,Stocchi Fabrizio

Funder

NIH

Canadian Institutes of Health Research

Parkinson Study Group

Michael J. Fox Foundation

Pharma2B

National Parkinson Foundation (PPMI)

NINDS

MJFF

Northwestern Foundation

Civitas

Acorda

Biogen

Roche Neuroderm

NIH PCORI

Allergan

University Hospital Foundation

Chemical Heritage Foundation

Frankfurt/Main

German Ministry of Education and Health

IPF

National Parkinson Foundation

Accorda

Kyowa

US World Meds

Abbvie

Biotie/Acorda Therapeutics

Movement Disorders Society

NIH/NINDS

Rhythm

Sunovion

Zambon pharma

Zambon

UCB

Cynapsus

Sunovia

Chiesi

Britannia

Neuroderm

BIAL

Publisher

Elsevier BV

Subject

Neurology (clinical),Geriatrics and Gerontology,Neurology

Reference75 articles.

1. “On-off” effects in patients with Parkinson's disease on chronic levodopa therapy;Marsden;Lancet,1976

2. Long-term side-effects of levodopa;Barbeau;Lancet,1971

3. The clinical physiology of side effects in long-term L-DOPA therapy;Barbeau;Adv. Neurol.,1974

4. Aromatic amino acids and modification of parkinsonism;Cotzias;N. Engl. J. Med.,1967

5. The “on-off” response to chronic L-DOPA treatment of Parkinsonism;Sweet;Adv. Neurol.,1974

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