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Spherical Nucleic Acid Architecture Can Improve the Efficacy of Polycation-Mediated siRNA Delivery

  • Published:2018-09 Issue: Volume:12 Page:207-219
  • ISSN:2162-2531
  • Container-title:Molecular Therapy - Nucleic Acids
  • language:en
  • Short-container-title:Molecular Therapy - Nucleic Acids

Author:

Melamed Jilian R.,Kreuzberger Nicole L.,Goyal Ritu,Day Emily S.

Funder

National Institutes of General Medical Sciences of the NIH

Maximizing Investigators’ Research Award

NIH-NIGMS

NSF

State of Delaware

Department of Defense through a National Defense Science and Engineering Graduate Fellowship

University of Delaware Summer Scholars program

National Science Foundation REU through NSF REU site

Publisher

Elsevier BV

Subject

Drug Discovery,Molecular Medicine

Reference55 articles.

1. Knocking down barriers: advances in siRNA delivery;Whitehead;Nat. Rev. Drug Discov.,2009

2. Non-viral vectors for gene-based therapy;Yin;Nat. Rev. Genet.,2014

3. Knocking down disease: a progress report on siRNA therapeutics;Wittrup;Nat. Rev. Genet.,2015

4. Polyplex evolution: understanding biology, optimizing performance;Hall;Mol. Ther.,2017

5. Recent developments in nucleic acid delivery with polyethylenimines;Neuberg,2014

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