Engineering of near-PAMless adenine base editor with enhanced editing activity and reduced off-target
Author:
Funder
National Key Research and Development Program of China
Leading Talents Program of Guangdong Province
Publisher
Elsevier BV
Subject
Drug Discovery,Molecular Medicine
Reference31 articles.
1. Programmable base editing of A∗T to G∗C in genomic DNA without DNA cleavage;Gaudelli;Nature,2017
2. Base editing: precision chemistry on the genome and transcriptome of living cells;Rees;Nat. Rev. Genet.,2018
3. ClinVar: public archive of interpretations of clinically relevant variants;Landrum;Nucleic Acids Res.,2016
4. ClinVar: public archive of relationships among sequence variation and human phenotype;Landrum;Nucleic Acids Res.,2014
5. Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy;Ryu;Nat. Biotechnol.,2018
Cited by 9 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. The pAblo·pCasso self-curing vector toolset for unconstrained cytidine and adenine base-editing in Gram-negative bacteria;Nucleic Acids Research;2024-01-05
2. CRISPR/Cas9-mediated base editors and their prospects for mitochondrial genome engineering;Gene Therapy;2024-01-04
3. Optimization of base editors for the functional correction of SMN2 as a treatment for spinal muscular atrophy;Nature Biomedical Engineering;2023-12-06
4. Base editor screens for in situ mutational scanning at scale;Molecular Cell;2023-07
5. Genome- and transcriptome-wide off-target analyses of a high-efficiency adenine base editor in tomato;Plant Physiology;2023-06-14
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"全球学者库"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前全球学者库共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2023 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3