Limiting Thymic Precursor Supply Increases the Risk of Lymphoid Malignancy in Murine X-Linked Severe Combined Immunodeficiency-Reference-Cited by-同舟云学术

Limiting Thymic Precursor Supply Increases the Risk of Lymphoid Malignancy in Murine X-Linked Severe Combined Immunodeficiency

Published:2017-03 Issue: Volume:6 Page:1-14
ISSN:2162-2531
Container-title:Molecular Therapy - Nucleic Acids
language:en
Short-container-title:Molecular Therapy - Nucleic Acids

Author:

Ginn Samantha L.,Hallwirth Claus V.,Liao Sophia H.Y.,Teber Erdahl T.,Arthur Jonathan W.,Wu Jianmin,Lee Hong Ching,Tay Szun S.,Hu Min,Reddel Roger R.,McCormack Matthew P.,Thrasher Adrian J.,Cavazzana Marina,Alexander Stephen I.,Alexander Ian E.

Funder

National Health & Medical Research Council (NHMRC) of Australia

Association for International Cancer Research

Clive and Vera Ramaciotti Foundation

The Wellcome Trust

National Institute for Health Research Biomedical Research Centre at Great Ormond Street Hospital for Children NHS Foundation Trust

University College London

The Kids Cancer Alliance

Publisher

Elsevier BV

Subject

Drug Discovery,Molecular Medicine

Reference53 articles.

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3. Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1;Hacein-Bey-Abina;J. Clin. Invest.,2008

4. Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients;Howe;J. Clin. Invest.,2008

5. Lymphomagenesis in SCID-X1 mice following lentivirus-mediated phenotype correction independent of insertional mutagenesis and gammac overexpression;Ginn;Mol. Ther.,2010

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