CYR61/CCN1: A Novel Mediator of Redox Response in Corneal Stromal Cells of Keratoconus

Author:

Liu Xiaoxue,Zhang Xiaowen,Li Qinghua,Wei Chaoqun,Guo Xinghan,Zhao Longfei,Liu Ting,Bao Qingdong,Dou ShengqianORCID,Seitz Berthold,Hua GaoORCID

Publisher

Elsevier BV

Reference38 articles.

1. Thrombin alters the synthesis and processing of CYR61/CCN1 in human corneal stromal fibroblasts and myofibroblasts through multiple distinct mechanisms;Andreae;Mol Vis,2020

2. In Vitro Expression Analysis of Cytokines and ROS-Related Genes in Human Corneal Fibroblasts and Keratocytes of Healthy and Keratoconus Corneas;Berger;Ocular Immunology and Inflammation,2024

3. The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling;Borkham-Kamphorst;Biochimica et Biophysica Acta (BBA) - Molecular Cell Research,2014

4. Incidence and Prevalence of Keratoconus Based on Scheimpflug Imaging;Chan;Ophthalmology,2023

5. New Keratoconus Risk Factors: A Cross-Sectional Case-Control Study;Debourdeau;J J Ophthalmol,2022

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