Circulating anti-β 2 -glycoprotein I antibodies of peripheral arterial disease patients trigger a genomic overexpression of Toll-like receptor 4 in endothelial cells

Author:

Varela Cesar,de Haro Joaquin,Bleda Silvia,Rodriguez-Padilla Javier,Ferruelo Antonio,Acín Francisco

Publisher

Elsevier BV

Subject

Cardiology and Cardiovascular Medicine,Surgery

Reference39 articles.

1. Beta2-glycoprotein: a plasma inhibitor of the contact activation of the intrinsic blood coagulation pathway;Schousboe;Blood,1985

2. Beta2-glycoprotein I (apo H) inhibits the release reaction of human platelets during ADP-induced aggregation;Nimpf;Atherosclerosis,1987

3. The anti-beta2-glicoprotein I activity in human anti-phospholipid syndrome sera is due to monoreactive low-affinity autoantibodies directed to epitopes located on native beta2-glycoprotein I and preserved during species evolution;Tincani;J Immunol,1996

4. Beta2-glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome;Agar;Blood,2010

5. Association between the valine/leucine247 polymorphism of β2-glycoprotein I and susceptibility to anti-phospholipid syndrome: a meta-analysis;Lee;Lupus,2012

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