Vardenafil: structural basis for higher potency over sildenafil in inhibiting cGMP-specific phosphodiesterase-5 (PDE5)
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Cellular and Molecular Neuroscience
Reference14 articles.
1. [3H]sildenafil binding to phosphodiesterase-5 is specific;Corbin;Mol. Pharmacol.,2003
2. Cyclic GMP phosphodiesterase-5: target of sildenafil;Corbin;J. Biol. Chem.,1999
3. Pharmacology of phosphodiesterase-5 inhibitors;Corbin;Int. J. Clin. Pract.,2002
4. Phosphorylation of phosphodiesterase-5 by cyclic nucleotide-dependent protein kinase alters its catalytic and allosteric cGMP-binding activities;Corbin;Eur. J. Biochem.,2000
5. Allosteric sites of phosphodiesterase-5 (PDE5). A potential role in negative feedback regulation of cGMP signaling in corpus cavernosum;Gopal;Eur. J. Biochem.,2001
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