Effects of delipidated serum and lipoprotein-deficient serum on sterol biosynthesis and efflux in cultured skin fibroblasts—a comparison of the behaviour of cells from a control with those from a heterozygote and homozygote for familial hypercholesterolaemia

Author:

Giles P.M.,Andrews B.J.,Cheshire J.,Noble Nancy,Muller D.P.R.,Slack Joan,Wolff O.H.

Publisher

Elsevier BV

Subject

Biochemistry, medical,Clinical Biochemistry,Biochemistry,General Medicine

Reference33 articles.

1. The inheritance of essential familial hypercholesterolaemia;Khachadurian;Am. J. Med.,1964

2. The familial hyperlipoprotcinacmias;Fredrickson,1978

3. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts by lipoproteins;Brown,1973

4. Familial hypercholesterolaemia: Defective binding of lipoproteins to cultured fibroblasts associated with improved regulation of 3-hydroxy-3-methyl glutaryl coenzyme A reductase activity;Brown,1974

5. Esterification of low density lipoprotein cholesterol in human fibroblasts and its absence in homozygous familial hypercholesterolemia;Goldstein,1974

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