Rationale and design of a randomised phase III registration trial investigating finerenone in participants with type 1 diabetes and chronic kidney disease: The FINE-ONE trial

Author:

Heerspink Hiddo J.L.,Birkenfeld Andreas L.ORCID,Cherney David Z.I.,Colhoun Helen M.ORCID,Ji Linong,Mathieu Chantal,Groop Per-Henrik,Pratley Richard E.,Rosas Sylvia E.,Rossing PeterORCID,Skyler Jay S.ORCID,Tuttle Katherine R.ORCID,Lawatscheck Robert,Scott Charlie,Edfors Robert,Scheerer Markus F.,Kolkhof PeterORCID,McGill Janet B.

Funder

Bayer

Publisher

Elsevier BV

Subject

Endocrinology,General Medicine,Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference36 articles.

1. Frequency and phenotype of type 1 diabetes in the first six decades of life: a cross-sectional, genetically stratified survival analysis from UK Biobank;Thomas;Lancet Diabetes Endocrinol,2018

2. IDF Diabetes Atlas. Type 1 diabetes estimates in children and adults. 2022. https://diabetesatlas.org/atlas/t1d-index-2022/ [Accessed 5 July 2023].

3. CKD prevalence and risk are higher in adults with type 2 vs. type 1 diabetes-an assessment of 1.5 million patients recently evaluated in U.S. clinical practices;Cressman;Diabetes,2018

4. Diabetic kidney disease: from physiology to therapeutics;Mora-Fernández;J Physiol,2014

5. Cumulative kidney complication risk by 50 years of type 1 diabetes: The effects of sex, age, and calendar year at onset;Costacou;Diabetes Care,2018

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