An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2-Reference-Cited by-同舟云学术

An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2

Published:2019-07 Issue: Volume:127 Page:512-526
ISSN:0969-9961
Container-title:Neurobiology of Disease
language:en
Short-container-title:Neurobiology of Disease

Author:

Connor-Robson Natalie^ORCID,Booth Heather,Martin Jeffrey G.,Gao Benbo,Li Kejie,Doig Natalie,Vowles Jane,Browne Cathy,Klinger Laura,Juhasz Peter,Klein Christine,Cowley Sally A.,Bolam Paul,Hirst Warren,Wade-Martins Richard

Funder

Parkinson's UK

Monument Trust Discovery Award

National Institute for Health Research

Oxford University Hospitals NHS Trust

University of Oxford

NIHR Comprehensive Local Research Network

Wellcome Trust

Oxford Martin School

Innovative Medicines Initiative

European Union's Seventh Framework Programme

Medical Research Council

Hermann and Lilly Schilling Foundation

Publisher

Elsevier BV

Subject

Neurology

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4. LRRK2 functions in synaptic vesicle endocytosis through a kinase-dependent mechanism;Arranz;J. Cell Sci.,2014

5. LRRK2 overexpression alters glutamatergic presynaptic plasticity, striatal dopamine tone, postsynaptic signal transduction, motor activity and memory;Beccano-Kelly;Hum. Mol. Genet.,2015

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