Inhibition of the mitochondrial pyruvate carrier in astrocytes reduces amyloid and tau accumulation in the 3xTgAD mouse model of Alzheimer's disease

Author:

Ceyzériat Kelly,Badina Aurélien M.,Petrelli Francesco,Montessuit Sylvie,Nicolaides Alekos,Millet Philippe,Savioz Armand,Martinou Jean-Claude,Tournier Benjamin B.

Funder

Swiss National Science Foundation

Publisher

Elsevier BV

Reference85 articles.

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4. Memory modulation by exercise in young adults is related to lactate and not affected by sex or BDNF polymorphism;Ballester-Ferrer;Biology (Basel).,2022

5. Deficits in mitochondrial function and glucose metabolism seen in sporadic and familial Alzheimer’s disease derived astrocytes are ameliorated by increasing hexokinase 1 expression;Bell;bioRxiv,2023

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