1. School of Biology and Biochemistry, The Queen's University of Belfast, Belfast BT9 7BL, Northern Ireland, UK
2. Molecular Pathology Laboratory, Royal Group of Hospitals Trust, Belfast BT12 6BL, Northern Ireland, UK
3. School of Medicine, The Queen's University of Belfast, Belfast BT9 7BL, Northern Ireland, UK
4. Molecular Medicine Program, Mayo Clinic, Guggenheim 18, Rochester, MN 55905, USA