Isolation and molecular characterization of Fikirini rhabdovirus, a novel virus from a Kenyan bat

Author:

Kading Rebekah C.1,Gilbert Amy T.2,Mossel Eric C.1,Crabtree Mary B.1,Kuzmin Ivan V.2,Niezgoda Michael2,Agwanda Bernard3,Markotter Wanda4,Weil M. Ryan56,Montgomery Joel M.7,Rupprecht Charles E.2,Miller Barry R.1

Affiliation:

1. Centers for Disease Control and Prevention, Division of Vector-borne Diseases, Arbovirus Diseases Branch, Fort Collins, CO, USA

2. Centers for Disease Control and Prevention, Division of High Consequence Pathogens and Pathology, Poxvirus and Rabies Branch, Atlanta, GA, USA

3. National Museums of Kenya, Nairobi, Kenya

4. University of Pretoria, Department of Microbiology and Plant Pathology, Pretoria, South Africa

5. Centers for Disease Control and Prevention, Office of Infectious Disease, National Center for Emerging and Zoonotic Infectious Diseases, Atlanta, GA, USA

6. SRA International, Atlanta, GA, USA

7. Centers for Disease Control and Prevention, Global Disease Detection Program, Nairobi, Kenya

Abstract

Zoonotic and vector-borne pathogens have comprised a significant component of emerging human infections in recent decades, and bats are increasingly recognized as reservoirs for many of these disease agents. To identify novel pathogens associated with bats, we screened tissues of bats collected in Kenya. Virus isolates were identified by next generation sequencing of viral nucleic acid preparations from the infected cell culture supernatant and characterized. Here we report the identification of Fikirini rhabdovirus, a novel rhabdovirus isolated from a bat, Hipposideros vittatus, captured along the Kenyan coast.

Publisher

Microbiology Society

Subject

Virology

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