Affiliation:
1. Institute of Microbiology, Technikerstrasse 25, A-6020 Innsbruck, Austria
Abstract
Excretion of organic acids, e.g. citrate, by anamorphic fungi is a frequent phenomenon in natural habitats and in laboratory cultures. In biotechnological processes for citrate production withAspergillus nigerextracellular citrate concentrations up to 1 mol l−1are achieved. Intracellular citrate concentrations are in the millimolar range. Therefore the question arises whether citrate excretion depends on active transport. In this article thermodynamic calculations are presented for citrate excretion byA. nigerat an extracellular pH of 3 and byPenicillium simplicissimumat an extracellular pH of 7. From the results of these calculations it is concluded that in both cases a passive transport step suffices for citrate excretion.
Cited by
18 articles.
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