Author:
del Rosario Sánchez Valerio María
Abstract
Sjogren’s syndrome (Sicca Syndrome) is mainly characterized by the presence of dry eye disease (DED). The diagnosis of DED in patients with Sjogren’s syndrome has been limited to tests such as the Schirmer test, tear breakup time (TBUT), and corneal stains; however, currently we can evaluate the functional unit in detail lacrimal, which is affected in patients with dry eye and Sjögren’s syndrome; thanks to technology that provides objective details for this difficult diagnostic. The newer evaluations that provide the greatest diagnostic value for Sjogren’s syndrome are: noninvasive keratograph tear rupture time (NIKBUT), tear meniscus height (TMH), Schirmer’s test, meibography, ocular surface disease index (OSDI), Vital stains of the ocular surface, Matrix Metalloproteinase 9 (MMP-9), Tear osmolarity (TearLab); all of these are important complements to the existing tests, which, although less objective, are not substitutable.
Reference92 articles.
1. Mariette X, Criswell LA. Primary Sjögren's syndrome. The New England Journal of Medicine. 2018;378:931
2. Wang X, Bootsma H, Terpstra J, et al. Progenitor cell niche senescence reflects pathology of the parotid salivary gland in primary Sjögren's syndrome. Rheumatology (Oxford). 2020;59:3003
3. Vivino FB, Bunya VY, Massaro-Giordano G, et al. Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment. Clinical Immunology. 2019;203:81
4. Kassan SS, Moutsopoulos HM. Clinical manifestations and early diagnosis of Sjögren syndrome. Archives of Internal Medicine. 2004;164:1275-1284
5. Retamozo S, Acar-Denizli N, Rasmussen A, Horváth IF, Baldini C, Priori R, et al. Systemic manifestations of primary Sjögren’s syndrome out of the ESSDAI classification: Prevalence and clinical relevance in a large international, multi-ethnic cohort of patients. Clinical and Experimental Rheumatology. 2019;37:97-106
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献