Management of Cervical Cancer and Human Papillomavirus in Pregnancy

Author:

Fernanda Calderón León María,Eugenia Ugarte Vega María,Elizabeth Yugcha Andino Germania,Andrea Vásquez Jaramillo Paula,Arturo Vélez Sáenz Germán,Paul Vargas Caicedo Joel,Elizabeth Pazmiño Iñiga Moraima,Guillermo Chong Viteri Alfredo,María Apolo Montero Angélica,del Carmen Quisiguiña Jarrín Nataly

Abstract

Cervical cancer during pregnancy is the most commonly detected malignant tumor. It has become a public health problem, 99% related to human papillomavirus (HPV) infection, making it the only gynecological malignant tumor of clear etiology in the world. It is diagnosed at any stage of pregnancy. Its initial presentation is observed as transvaginal bleeding in all three trimesters associated with HPV infection. If the metastasis is negative in the lymph nodes, it improves. At an early stage the prognosis is favorable, management consists of preserving pregnancy, neoadjuvant chemotherapy can be used to treat cervical cancer in pregnancy, in cases of viable pregnancies between 27- and 31-weeks’ gestation chemotherapy may be performed depending on the staging, caesarean section at 35 weeks, radical surgery and systemic chemotherapy may achieve good results depending on the stage of the tumor.

Publisher

IntechOpen

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