Phytosomes as a Novel Approach to Drug Delivery System

Author:

Kumar Vishwakarma Dhaneshwar,Narayan Mishra Jai,Kumar Shukla Amit,Pratap Singh Abhay

Abstract

“Phyto” refers to a plant, whereas “some” refers to something that looks like a cell. The other term for it is herbosomes. This is a brand-new, patented technique that mixes phospholipids with systematic herbal extracts or moisture phytocomponents to produce lipid-consistent tiny composites that significantly increase absorption and bioavailability. Phosphatidylcholine, phosphatidylinositol, phosphatidylserine, and phosphatidylethanolamine are frequently used phospholipids. Plant-derived therapies have gained notoriety and acceptance in the worldwide drug trade as safe and effective alternatives to contemporary synthetic medications as a result of their complex and unpleasant interactions. According to World Health Organization (WHO), more than 80% of people around the world believe in herbal remedies. Active ingredients originating from plants have been used to treat a number of diseases since the dawn of time. Natural plant extracts that are active have been proven to have strong pharmacological effects in vitro but limited in vivo absorption. Poor absorption has been addressed in a number of ways, including the creation of emulsions, liposomes, and nanoparticles, as well as the alteration of chemical structures and administration as prodrugs. Phytophospholipid complexes, also known as phytosomes, have emerged as a promising tactic to increase the bioavailability of active ingredients among the possible approaches.

Publisher

IntechOpen

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