Jatroidaine A: a New Tetranortirucallane Type Triterpene from Jatropha multifida
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Published:2021-05-08
Issue:5
Volume:15
Page:408-413
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ISSN:1307-6167
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Container-title:Records of Natural Products
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language:
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Short-container-title:Rec.Nat.Prod.
Author:
Li Fei,Ma Liang,Zhang Jinyuan,Qiao Xueling,Zhang Dingshan,Zhang Dongbo
Abstract
Jatroidaine A (1), a new tetranortirucallane-type triterpene, and two known analogues (2−3) were isolated from the leaves and branches of Jatropha multifida. Their structures were fully elucidated by extensive spectroscopic methods and comparison to known compounds. The absolute configuration of 1 was assigned by single-crystal X-ray diffraction analysis. All compounds were evaluated for their anti-inflammatory and thioredoxin reductase (TrxR) inhibitory activities. Unfortunately, no significant activity was observed.
Publisher
ACG Publications
Subject
Organic Chemistry,Plant Science,Drug Discovery,Pharmacology