Cobalt(II) catalytic oxidation of arylmethyl sulfonyl imines to arylcarbonyl analogues

Author:

Ma Zetao,Ma Peipei,Wu Hongli,Gan HaifengORCID

Abstract

A novel Co(OAc)2/N-hydroxyphthalimide (NHPI)-catalyzed oxidation of 3-arylmethyl sulfonyl imines to prepare 3-arylcarbonyl analogues has been realized. 3-Arylcarbonyl sulfonyl imines were comprehensively synthesized from benzyl substrates for the first time. The reactions proceeded in moderate to excellent yields. Mechanistic investigation suggests that 3-(hydroperoxy(phenyl)methyl)benzo[d]isothiazole 1,1-dioxide A is the key intermediate for the formation of products 2.

Publisher

CSIRO Publishing

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