Abstract
The leaves of Acronychia baueri Schott.
contain the acridine alkaloids melicopine, melicopidine, and melicopicine and
the furoquinolines skimmianine, acronycidine, and kokusaginine, the structures
of which have all been established previously. In addition two new alkaloids
are present. These are 2,4-dimethoxy-10-methylacridone (I) and a
dimethoxydimethylpyranofuroquinoline which has been named acronidine.
Acronidine has been degraded to a phenol which on methylation gives
isokokusaginine (II). The alkaloid must therefore possess structure III or IV,
the latter being preferred.
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