Functional Biomaterials: Design of Novel Biomaterials

Author:

Sakiyama-Elbert SE12,Hubbell JA12

Affiliation:

1. Department of Biomedical Engineering, Washington University, St. Louis, Missouri 63130-4899;

2. Institute for Biomedical Engineering and Department of Materials, Swiss Federal Institute of Technology and University of Zurich, CH-8044 Zurich, Switzerland;

Abstract

▪ Abstract  The field of biomaterials has recently been focused on the design of intelligent materials. Toward this goal, materials have been developed that can provide specific bioactive signals to control the biological environment around them during the process of materials integration and wound healing. In addition, materials have been developed that can respond to changes in their environment, such as a change in pH or cell-associated enzymatic activity. In designing such novel biomaterials, researchers have sought not merely to create bio-inert materials, but rather materials that can respond to the cellular environment around them to improve device integration and tissue regeneration.

Publisher

Annual Reviews

Subject

General Materials Science

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