Affiliation:
1. SBEI HPE “South-Ural State Medical University” of the Ministry of Health. Chelyabinsk, Russia
Abstract
Aim. To study gender specifics of structural and functional parameters of brachiocephal arteries with the relation to psychoemotional factors in almost healthy individuals.Material and Methods. Overall 107 almost healthy economically active individuals included from organized population (46 male, 61 female), with the average age 43,4±10,8 y. All participants underwent psychological testing that included questionnaires: Spolberger-Khanin test, depression evaluation scale by the Center for Epidemiological Studies, visualanalogue scale (modified Dembo-Rubinstein), the social frustration level, social adaptation test by Holmes-Rey, ultrasound scanning of brachiocephal arteries with evaluation of local rigidity parameters.Results. There were significant gender differences found for the vessel wall structural and functional parameters. Average values of systolic and diastolic diameters, total common carotid artery wall thickness were higher in males, but the rigidity index - in women. Prevalence of personal anxiety and clinically significant stress estimates by the Holmes-Rey scale was significantly higher in women, 75% and 36%, resp. In both groups the association of psycho-emotional factors and vessel parameters was found. But for men there was independent relation of reactive and personal anxiety with the thickness of “intima-media” and in women – correlation of depression and vessel wall compliance.Conclusion. The results direct to the need for further research of novel methods for complex primary prophylaxy of stress-induced remodeling of vessels with the connection to psychoemotional and gender specifics.
Subject
Cardiology and Cardiovascular Medicine
Reference13 articles.
1. Kiseleva MG. Psychological factors and course of cardio-vascular diseases. National Psychological J 2012; 1 (7): 124–30. Russian (Kiseleva M. G. Psikhologicheskie faktory i techenie serdechno-sosudistykh zabolevanii. Natsional'nyi psikhologicheskii zhurnal 2012; 1 (7): 124–30).
2. Sumin AN, Sumina LJu, Barbarash NA. Stressful hemodynamic changes in type D personality in healthy young adults. Cardiovascular Therapy and Prevention 2012; 11 (3): 70–6. Russian (Sumin A. N., Sumina L. Yu., Barbarash N. A. Stressornye izmeneniya gemodinamiki pri tipe lichnosti D u zdorovykh lits molodogo vozrasta. Kardiovaskulyarnaya terapiya i profilaktika 2012; 11 (3): 70–6).
3. Shavrin AP, Hovaeva JaB., Golovskoj BV. The value of psycho-emotional factors in the development of immune deficiency, infection with the organism and changes of the vascular wall in otherwise healthy individuals with risk factors. Cytokines and Inflammation 2010; 9 (4):23–7. Russian (Shavrin A. P., Khovaeva Ya. B., Golovskoi B. V. Znachenie psikhoemotsional'nykh faktorov v razvitii immunnoi nedostatochnosti, infitsirovanii organizma i izmenenii sosudistoi stenki u prakticheski zdorovykh lits s faktorami riska. Tsitokiny i vospalenie 2010; 9 (4): 23–7).
4. Poli A, Tremoli E, Colombo A, et al. Ultrasonographic measurement of the common carotid artery wall thickness in hypercholesterolemic patients: a new model for the quantification and follow-up of pre-clinical atherosclerosis in living human subjetcs. Atherosclerosis 1988; 70: 253–61.
5. Laurent S, Cockcroft J, Van Bortel L, et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J 2006; 27 (21): 2588–605.