Combination of Takotsubo cardiomyopathy with cardiac myxoma: a case report

Abstract

Introduction. In the Russian literature, we have not found data on the combination of takotsubo syndrome (TTS) and left atrial (LA) myxoma. The work analyzed our own clinical case. TTS is diagnosed in 1,0-2,5% of patients hospitalized with suspected acute coronary syndrome (ACS). Primary cardiac tumors occur in cardiology with a frequency of up to 0,2%. The most common of them are LA myxoma.Brief description. The patient was admitted to the clinic with suspected ACS. During the diagnostic search, both ACS and acute myocarditis were ruled out. An incidental finding during an echocardiographic study was LA myxoma.Discussion. Due to a stressful situation, the patient developed symptoms similar to myocardial infarction. Based on coronary angiography data (normal coronary arteries, rapid restoration of myocardial contractility, no characteristic myocardial changes, myocardial infarction and acute myocarditis were excluded and TTS was established. LA myxoma was an unexpected finding.Myxoma may contribute to TTS, presumably through central mechanisms regulating the activity of the cardiovascular system. Also important is the systemic inflammation caused by myxoma, which reduces the threshold for the development of Takotsubo cardiomyopathy in response to stress factors.