AGE-RELATED ADAPTATION OF PORTAL HEMODYNAMICS IN RATS DURING 75 DAY FOLLOW-UP

Author:

Vinogradov Alexander A.,Andreeva Irina V.,Simakova Evgeniya S.

Abstract

The age-related adaptation of portal hemodynamics was studied in young rats by ultrasound methods. In the mode of color Doppler mapping, a color signal was visualized in the projection of the portal vein, and in the spectral Doppler mode, the spectrum of blood flow in the portal vein was visualized. The diameter and cross-section of the portal vein, linear and volumetric blood flow rates were determined. The study was performed at the beginning and after 60- and 75-day follow-up. It was found that the portal hemodynamics parameters were influenced by a change in the diameter of the portal vein. With an increase in the diameter of the portal vein, the linear velocity of blood flow in the portal vein decreased, but the volumetric velocity of blood flow in the portal vein increased. Conclusions. The mechanisms of age-related adaptation of portal hemodynamics include compensation for a decrease in the linear velocity of blood flow by increasing the volumetric velocity of blood flow in the portal vein.

Publisher

Volgograd State Medical University

Subject

Anesthesiology and Pain Medicine

Reference9 articles.

1. Liver hemodynamic flow balance by image directed Doppler ultrasound evaluation in normal subjects / L. Bombelli, V. Genitoni, S. Biasi [et al.] // Journal of Clinical Ultrasound. Gut. 1991. Vol. 30. P. 503-509. https://doi.org/10.1002/jcu.1870190502.

2. Андреева И.В., Виноградов А.А. Перспективы использования современных методов визуализации в морфологических и экспериментальных исследованиях // Наука молодых. 2015. № 4. С. 59-69.

3. Андреева И.В., Виноградов А.А. Атлас нормальной и ультразвуковой анатомии живота крысы. М.: ГЭОТАР-Медиа, 2015. 175 с.

4. Лелюк В.Г., Лелюк С.Э. Ультразвуковая ангиология. Москва: Реальное время, 2003. 336 с. URL: http://medobook.com/3378-ultrazvukovaya-angiologiya-lelyuk-vg-lelyuk-se-2003-g.html.

5. Современные возможности изучения гемодинамики в экспериментальных исследованиях / И.В. Андреева, А.А. Виноградов, Т.М. Жесткова [и др.] // Дальневосточный медицинский журнал. 2019. № 2. С. 54-58. https://doi.org/10.35177/1994-5191-2019-1-54-58.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3