Plasminogen activator inhibitor-1 does not contribute to the pulmonary pathology induced by acute exposure to ozone

Author:

Elkhidir Hamza S.1,Richards Jeremy B.2,Cromar Kevin R.3,Bell Cynthia S.4,Price Roger E.5,Atkins Constance L.6,Spencer Chantal Y.7,Malik Farhan1,Alexander Amy L.8,Cockerill Katherine J.8,Haque Ikram U.1,Johnston Richard A.189

Affiliation:

1. Division of Critical Care Medicine; Department of Pediatrics; McGovern Medical School at The University of Texas Health Science Center at Houston; Houston Texas

2. Division of Pulmonary; Critical Care and Sleep Medicine; Department of Medicine; College of Medicine; Medical University of South Carolina; Charleston South Carolina

3. Department of Environmental Medicine; New York University School of Medicine; Tuxedo New York

4. Division of Nephrology; Department of Pediatrics; McGovern Medical School at The University of Texas Health Science Center at Houston; Houston Texas

5. Comparative Pathology Laboratory; Center for Comparative Medicine; Baylor College of Medicine; Houston Texas

6. Division of Pulmonary Medicine; Department of Pediatrics; McGovern Medical School at The University of Texas Health Science Center at Houston; Houston Texas

7. Section of Pediatric Pulmonology; Department of Pediatrics; Baylor College of Medicine; Houston Texas

8. Pediatric Research Center; Department of Pediatrics; McGovern Medical School at The University of Texas Health Science Center at Houston; Houston Texas

9. Department of Integrative Biology and Pharmacology; McGovern Medical School at The University of Texas Health Science Center at Houston; Houston Texas

Funder

National Institute of Environmental Health Sciences

National Institute of Allergy and Infectious Diseases

Publisher

Wiley

Subject

Physiology (medical),Physiology

Reference76 articles.

1. Administration on Aging 2015 Future growth. The Administration on Aging, Washington, D.C. Available at http://www.aoa.acl.gov/Aging_Statistics/Profile/2014/4.aspx

2. Mechanisms contributing to the conformational and functional flexibility of plasminogen activator inhibitor-1;Aertgeerts;Nat. Struct. Biol.,1995

3. Neither fibrin nor plasminogen activator inhibitor-1 deficiency protects lung function in a mouse model of acute lung injury;Allen;Am. J. Physiol. Lung Cell. Mol. Physiol.,2009

4. Alveolar protein accumulation. A sensitive indicator of low level oxidant toxicity;Alpert;Arch. Intern. Med.,1971

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