Salivary Interleukin 1-beta levels and clinical periodontal parameters in habitual naswar users and non-users

Abstract

Objectives: Aim of our study was to assess the expression of salivary Interleukin 1-beta (IL-1β) and clinical periodontal parameters in naswar users and non-users (controls). Methods: Eighty four individuals (forty-two naswar users and forty-two controls) were included in the study which was conducted between August 2017 and May 2018. Salivary IL-1β levels, plaque index (PI), bleeding on probing (BOP), probing depth (PD) and clinical attachment loss (CAL) was assessed in all the participants. Results: PD of 4mm (p<0.05), PD of 5-6mm (p<0.05), CAL (p<0.001) and levels of salivary IL1β (p<0.05) were significantly higher among naswar users as compared to controls while PI, BOP and number of missing teeth showed no significant difference among the two groups (p>0.05). Conclusion: Periodontal inflammatory conditions were worse and salivary IL-1β levels were elevated in naswar users as compared to controls. doi: https://doi.org/10.12669/pjms.35.3.10 How to cite this:Abbasi ZA, Hadi NI, Zubairi AM, Hosein M. Salivary Interleukin 1-beta levels and clinical periodontal parameters in habitual naswar users and non-users. Pak J Med Sci. 2019;35(3):674-679. doi: https://doi.org/10.12669/pjms.35.3.10 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.