Stabilization of the disease as an important factor in the evaluation of the effectiveness of treatment and prognosis of survival for cancer patients

Abstract

Currently, the effectiveness of treatment is assessed by Response Evaluation Criteria In Solid Tumors (RECIST) criteria. The stabilization of the disease is the one of the results of the treatment. This term means a slight growth or regression of the tumor without the appearance of new lesions, when it is impossible to assign these changes neither to the progression of the disease nor to partial regression, but in any case stabilization of disease is evaluated as ineffective treatment. But the stabilization of the disease often leads to the improvement of the quality of life, slowdown in the growth of the tumor and metastasis and thereby to the win in terms of life expectancy. The purpose of the study. A study of the concept of ‘stabilization of the disease ’ as a criterion that determines the control of tumor growth. Methods. There was performed an analysis of various scientific works on the study of the efficiency of the treatment of solid tumors: ovarian cancer, small-cell lung cancer (SCLC), non small-cell lung cancer (NSCLC), colon cancer, prostate cancer, breast cancer. Conclusion. Stabilization of the disease is an important criterion for the evaluation of the antitumor treatment in patients and has the important prognostic value.