Idiopathic gastro-duodenal ulcers.-Reference-Cited by-同舟云学术

Idiopathic gastro-duodenal ulcers.

Published:2018-12-20 Issue:8 Volume:96 Page:702-706
ISSN:2412-1339
Container-title:Clinical Medicine (Russian Journal)
language:
Short-container-title:Klin. med.

Author:

Sheptulin A. A.I.¹,Kardasheva S. S.¹,Beer A.²

Affiliation:

1. T. M. Sechenov First Moscow State Medical University (Sechenovsky University)

2. Ludwig Maximilian University

Abstract

Idiopathic gastroduodenal ulcers (IGD) are stomach and duodenal ulcers not associated with Helicobacter pylori infection or with the administration of non-steroidal anti-inflammatory drugs. Their relative frequency ranges from 1.6 to 35%, and is likely to be overestimated due to frequent false negative test results. The etiology and pathogenesis of IGDH remain poorly understood. Factors contributing to their development can serve as old age, hereditary predisposition, disorders of gastric mucus, mesenteric ischemia. Compared to the positive peptic ulcer disease, PYLORI is characterized by less favorable course, higher frequency of gastrointestinal bleeding (including repeated), slow healing, more frequent recurrence. Treatment of IGD involves long-term use of proton pump inhibitors (PPI).

Publisher

Medical Informational Agency Publishers

Subject

General Medicine

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