Delayed reperfusion for saving vital myocardium in the acute period of myocardial infarction with elevation of ST segment-Reference-Cited by-同舟云学术

Delayed reperfusion for saving vital myocardium in the acute period of myocardial infarction with elevation of ST segment

Published:2016-06-01 Issue:4 Volume:94 Page:307-312
ISSN:2412-1339
Container-title:Clinical Medicine (Russian Journal)
language:
Short-container-title:Klin. med.

Author:

Gazaryan Georgi G.¹

Affiliation:

1. N.V. Sklifosovsky Research Institute of Emergency Medicine

Abstract

Reperfusion therapy in case of acute myocardial infarction is especially desirable within 12 hr afterfirst clinical manifestations as shown in studies with the use of thrombolytic therapy (TLT). Its efficiency for saving ischemic myocardium decreases as the time from the onset of pain syndrome increases. Nevertheless, patients admitted to the clinic in the period deemed unfavourable for TLT still preserve large part of vital myocardium even if in the risk zone. Delayed saving myocardium impossible by TLT can be ensured by transdermal coronary interventions. The dependence of myocardial necrosis on the duration of occlusion of the coronary artery is as well recognized as the necessity of early interventions. Transdermal coronary interventions can be performed within days 2 or 3 after onset of acute myocardial infarction if it was impracticable in an earlier period.

Publisher

Medical Informational Agency Publishers

Subject

General Medicine

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