Characteristic of adhesive properties of endothelium and subendothelial structures of aortic vlve in patients with calcific aortic stenosis-Reference-Cited by-同舟云学术

Characteristic of adhesive properties of endothelium and subendothelial structures of aortic vlve in patients with calcific aortic stenosis

Published:2017-06-06 Issue:4 Volume:95 Page:350-354
ISSN:2412-1339
Container-title:Clinical Medicine (Russian Journal)
language:
Short-container-title:Klin. med.

Author:

Gulyaev N. I.¹,Zhukov M. V.²,Golubok A. O.²,Kuranov G. L.³,Borisov Yu. A.⁴,Suglobova E. D.⁴,Kuznetsov V. V.¹,Peremyshlenko A. S.¹,Gordienko A. V.¹,Kostina O. V.¹

Affiliation:

1. S.M. Kirov Military Medical Academy

2. National Research University of Information Technologies, Mechanics and Optics; Institute of Analytical Instrument Engineering

3. Sankt-Peterburg State University

4. I.P.Pavlov First Sankt-Peterburg State Medical University

Abstract

The article presents results of research on adhesive properties of aortic crescents (endothelial and subendothelial surface) obtained with the use of atomic force microscopy and specially created hydroxyapatite-based probes along with results of identification of the chemical composition of deposited calcium salts in patients with calcified aortic stenosis. The results of the study are supposed to be of pathogenetic significance for understanding the development of calcified aortic stenosis. The proposed method for creating specialized probes for atomic force microscopy can be used in the modeling of processes of ectopic calcification of other organs and system.

Publisher

Medical Informational Agency Publishers

Subject

General Medicine

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