Author:
Kovalenko O.Y.,Prityko N.G.
Abstract
Relevance: The problem of treatment of cerebrovascular diseases is one of the leading in modern medicine. The combination of this nosology in patients with emotional and volitional disorders acquires a special shade. Features of neurochemical transmission of impulses in different hemispheres of the brain provide greater opportunities for improving the treatment of patients with chronic cerebral venous dysfunction syndrome (SCVD).
Objective: To study the features of hemispheric lateralization of the brain in patients with SCVD and indicators of anxiety on the Spielberger-Khanin scale and depression on the Beck scale. Materials and methods: 153 patients tested on the scale of reactive (RT) and personal (LT) anxiety Spielberger-YL Khanin and Beck depression. 125 people with signs of SCCVD and various levels of BP. Mean age of patients: 53.60 ± 10.27 years, 115 women, 38 men. All underwent clinical and neurological examination, testing to determine hemispheric dominance on the scale of NP Rebrova and MP Chernysheva. Statistics were calculated using the Medstat program. The comparison was performed according to the criterion of W. Kruskal-A. Wallis, the criterion of J. Dunn and the chi-square. Results: It was found that the presence of SCCVD did not depend on hemispheric dominance. In patients with SCVD with left hemisphere lateralization, there was a statistically significant increase in personal anxiety on the Spielberger-Khanin scale (p<0.001). The patients with SCVD and right-hemispheric lateralization had a statistically significant increase in depression on the Beck scale (p <0.001). Patients of the control group did not show a statistically significant relationship between the types of hemispheric dominance and indicators of personal anxiety and depression.
Publisher
State Institution of Science Research and Practical Center
Reference13 articles.
1. Osborn`s Brain: Imaging, Pathology, and Anatomy (second edition), by Anne G. Osborn, Gary L. Hedlund, Karen L. Salzman. Elsevier; 2 edition (November 2, 2017) ISBN-13: 978-0323477765b, ISBN-10: 0323477763. 1300p.
2. Illarioshkin S.N., Kobrin V.I., Fokin V.F. Aktual'nye voprosy funkcional'noj mezhpolusharnoj asimmetrii i nejroplastichnosti. M.: Nauchnyj mir. 2008. 808 s.
3. Olulade, O. A., Seydell-Greenwald, A., Chambers, C. E., Turkeltaub, P. E., Dromerick, A. W., Berl, M. M., Gaillard, W. D. & Newport, E. L. (2020). The neural basis of language development: Changes in lateralization over age. Proceedings of the National Academy of Sciences, 117(38), 23477-23483.
4. Dobronravova I.S. Znachenie mezhpolusharnoj asimmetrii v razvitii kompensatornyh processov mozga cheloveka. Vysshaja nervnaja dejatel'nost'.1989. t.39. #5. S.819.
5. Reber, J., & Tranel, D. Sex differences in the functional lateralization of emotion and decision making in the human brain. Journal of Neuroscience Research, 95(1-2), 2017. 270-278.