Affiliation:
1. Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon, Maharashtra, India
Abstract
Anthelmintics are a class of antiparasitic drugs that eliminate parasitic worms (helminths) and other internal parasites from the body by stunning or destroying them without harming the host. They're also known as vermifuges (stun drugs) or vermicides (drugs that destroy vermin) (those that kill). Anthelmintics, a disease called helminthiasis, are used to treat individuals that are infected by helminths. For the care of infected animals, these medications are sometimes used. The extraction from leaves of Jasminum Grandiflorum and Cordia Dichotoma was done by soxhlet apparatus for 3 days by using alcohol (Ethanol) as solvent. After that the evaporation of solvent was done for obtaining solid form of extract. Phytochemical screening of solid form of extract was performed to study its contents ( Eg. Tannins, Alkaloids, Anthocynin, steroids, etc.)Cordia Dichotoma and Jasminum Grandiflorum extracts in ethanol were taken for anthelmintic activity against Parthitima Postuma which is an Indian earthworm. Various quantities of both extract were monitored and the results were expressed for paralysis and bacterial death time. Distilled water used as acontrol group. Dependent Activity of the dose of both plants was observed But Jasminum grandiflorum shows more activity than Cordia diachotoma .It was concluded that Both the studied plants had some anthelmintic activity, therefore, in vivo trials may be conducted for further.
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