HPV Infection and Vulvar Cancer

Abstract

Vulvar cancer is an uncommon gynecological malignancy primarily affecting postmenopausal women and is the fourth most common gynecologic cancer. There is no specific screening and the most effective strategy to reduce vulvar cancer incidence is the opportune treatment of predisposing and preneoplastic lesions associated with its development. Vulvar carcinoma can be HPV-positive or HPV- negative. Any suspicious vulvar lesion should be biopsied to exclude invasion.