Affiliation:
1. Chuvash State University
Abstract
Mast cells play an important role in many processes occurring in the human body. These include inflammation, allergic reactions, parasitic infections, carcinogenesis and others. Therefore, the detection of mast cells plays an important role in the diagnosis of pathological conditions. The purpose of the study is to summarize data on imaging methods of mast cells. Materials and methods. Review of available literature sources published in Elibrary and PubMed. Results. There are several major groups of methods for finding mast cells: histochemical, enzyme-linked histochemical and immunohistochemical. All are based on the ability to detect specific substances contained in mast cell granules. Histochemical methods include Unno, alcian blue and safranin staining of mast cells and others. The most modern method is mast cell visualisation using immunohistochemical reactions based on antigen-antibody reactions. Conclusion. This review presents the most common methods of mast cell staining, differing in difficulty of performance, specificity in relation to mast cells and staining cost.
Publisher
I.N. Ulianov Chuvash State University
Subject
Management Science and Operations Research,Mechanical Engineering,Energy Engineering and Power Technology
Reference59 articles.
1. Artashyan O.S., Khramtsova Yu.S., Tyumentseva N.V., Yushkov B.G., Chereshnev V.A. Tuchnye kletki miokarda i adaptatsiya serdtsa k fizicheskoi nagruzke [Cardiac mast cells and adaptation of the heart to physical activity]. Sport. Meditsina, 2021, vol. 21(2), pp. 34–41. DOI: 10.14529/hsm210204.
2. Atyakshin D.A. Gistohimicheskie podhody k ocenke uchastija v reguljacii sostojanija voloknistogo komponenta mezhkletochnogo matriksa soedinitel’noj tkani kozhi [Histochemical approaches to the evaluation of the participation of mast cells in the regulation of the fibrous component of the intercellular matrix of skin connective tissue]. Zurnal anatomii i gistopatologii, 2018, vol. 7(3), pp. 100–112. DOI: https://doi.org/10.18499/2225-7357-2018-7-3-100-112.
3. Bykov V.L. Sekretornye mehanizmy i sekretornye produkty tuchnyh kletok [Secretory mechanisms and secretory products of mast cells]. Morfologiia, 1999, vol. 115(2), pp. 64–72.
4. Gordova V.S., Ivanova E.P., Sergeeva V.E. Tuchnye kletki pri okraske toluidinovym sinim v eksperimente [Properties of toluidine blue stained mast cells in the experiment with the intake of soluble silicon]. Vestnik Baltiiskogo federal’nogo universiteta im. I. Kanta, 2018, no. 2, pp. 97–104.
5. Grigor’ev I.P., Korzhevskii D.E. Sovremennye tekhnologii vizualizatsii tuchnykh kletok dlya biologii i meditsiny (obzor) [Modern technologies of mast cell imaging for biology and medicine (review)]. Sovremennye tekhnologii v meditsine, 2021, vol. 13(4), pp. 93–109. DOI: https://doi.org/10.17691/stm2021.13.4.10.
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