1. 1Anesthesia and Intensive Care Medicine, IRCCS San Raffaele Scientific Institute, Milan, Italy; and Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.
2. 2Department of Anesthesiology and Intensive Care, ASST Santi Paolo e Carlo, University of Milan, Milan, Italy.
3. 3Department of Anesthesiology and Intensive Care, ASST Santi Paolo e Carlo, University of Milan, Milan, Italy.
4. 4Department of Anesthesiology and Intensive Care, ASST Santi Paolo e Carlo, University of Milan, Milan, Italy.
5. 5Guy’s and St. Thomas’ NHS Foundation Trust, Department of Adult Critical Care, London, United Kingdom.
6. 6Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany; and Outcomes Research Consortium, Cleveland, Ohio.
7. 7Department of Anesthesiology and Intensive Care, ASST Santi Paolo e Carlo, University of Milan, Milan, Italy.
8. 8Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.