Affiliation:
1. Pediatric Gastroenterology
2. Gastroentrology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Abstract
Blue rubber bleb nevus syndrome (BRBNS) is a rare congenital disorder presenting with multifocal venous malformations of the skin, soft tissues, and gastrointestinal (GI) tract. Patients usually present with chronic anemia resulting from occult GI bleeding and sometimes with massive GI bleeding. We report 2 children with blue rubber bleb nevus syndrome with GI bleeding: 1 with obscure GI bleeding and the other with overt GI bleeding. In both cases, the presence of cutaneous lesions provided useful clues toward diagnosis. Colonoscopy and upper GI endoscopy revealed bluish polypoidal lesions in the GI tract. Capsule endoscopy helped in disease mapping. Both of them were successfully treated with endoscopic band ligation and nonselective beta-blockers, which resulted in an improvement in their hemoglobin levels. Our cases highlight the successful use of endoscopic band ligation of GI lesions as a therapeutic modality. It is important for gastroenterologists to be aware of this rare condition for current diagnosis.
Subject
General Earth and Planetary Sciences,General Environmental Science
Reference12 articles.
1. Haemangiomata of the intestine.;Heycock;Br Med J,1951
2. Endoscopic sclerotherapy for esophageal hemangioma.;Narumiya;Gastrointest Endosc,2000
3. Case of nevus involving the parotid gland and causing death from suffocation: nevi of the viscera.;Gascoyen;Trans Pathol Soc Lond,1860
4. Blue rubber bleb nevus syndrome.;Oksuzoglu;Am J Gastroenterol,1996
5. Blue rubber bleb nevus syndrome: a case report and literature review.;Jin;World J Gastroenterol,2014