BIOMARKERS: CAN THEY REALLY GUIDE OUR DAILY PRACTICE?

Author:

Tsangaris Iraklis1,Antonakos Nikolaos2,Fantoni Massimo,Kaplanski Gilles3,Kyriazopoulou Evdoxia1,Veas Francisco,Clemens Mark4

Affiliation:

1. 2nd Department of Critical Care Medicine, Medical School, National and Kapodistrian University of Athens, Athens, Greece

2. 4th Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Athens, Greece

3. Division of Internal Medicine and Clinical Immunology, Hôpital de la Conception, C2VN-INSERM U1263, Aix-Marseille University, Marseille, France

4. Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, North Carolina

Abstract

ABSTRACT Optimal management of septic patients requires accurate assessment of both current severity status and prognosis. Since the 1990s, substantial advances have been made in the use of circulating biomarkers for such assessments. This summary of the session on “Biomarkers: can they really use guide our daily practice?” presented at the 2021 WEB-CONFERENCE OF THE EUROPEAN SHOCK SOCIETY, 6 November 2021. These biomarkers include ultrasensitive detection of bacteremia, circulating soluble urokina-type plasminogen activator receptor (suPAR), C-reactive protein (CRP) and ferritin and procalcitonin. In addition, the potential application of novel multiwavelength optical biosensor technology allows noninvasive monitoring of multiple metabolites that can be used to assess severity and prognosis in septic patients. The application these biomarkers and improved technologies provide the potential for improved personalized management of septic patients.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Critical Care and Intensive Care Medicine,Emergency Medicine

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