Forced Revision Can Still Inform—Lessons and Questions From the “Original” TWO Study
Author:
Affiliation:
1. Department of Medicine, Stanford University, Palo Alto, CA.
2. Geriatric Research and Education Clinical Center, Veterans Affairs (VA) Palo Alto Health Care System, Palo Alto, CA.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Reference5 articles.
1. Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.;Sawitzki;Lancet,2020
2. Late treatment with autologous expanded regulatory T cell therapy after alemtuzumab induction is safe and facilitates immunosuppression withdrawal in living donor renal transplantation.;Brook;Transplantation,2024
3. Transplantation Without Overimmunosuppression (TWO) study protocol: a phase 2b randomised controlled single-centre trial of regulatory T cell therapy to facilitate immunosuppression reduction in living donor kidney transplant recipients.;Brook;BMJ Open,2022
4. A phase I clinical trial with ex vivo expanded recipient regulatory T cells in living donor kidney transplants.;Mathew;Sci Rep,2018
5. Study design: human leukocyte antigen class I molecule A(*)02-chimeric antigen receptor regulatory T cells in renal transplantation.;Schreeb;Kidney Int Rep,2022
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