MEESSI-AHF score to estimate short-term prognosis of acute heart failure patients in the Emergency Department: a prospective and multicenter study

Author:

Oberlin Mathieu1,Buis Guillaume2,Alamé Karine1,Martinez Mikaël34,Bitard Marie Paule5,Berard Lise6,Losset Xavier7,Balen Frederic8,Lehodey Bruno9,Taheri Omide10,Delannoy Quentin11,Kepka Sabrina112,Tran Duc-Minh13,Bilbault Pascal114,Godet Julien1516,Le Borgne Pierrick114

Affiliation:

1. Emergency Department, University Hospitals of Strasbourg, Strasbourg

2. Emergency Department, Hospital of Mulhouse, Mulhouse

3. Emergency Department, Hospital of Forez, Montbrison

4. Emergency Network Urg-ARA 3 place Louis Pradel

5. Emergency Department, Hospital of Remiremont, Remiremont

6. Emergency Department, Hospital of Haguenau, Haguenau

7. Emergency Department, University Hospital of Reims, Reims

8. Emergency Department, University Hospital of Toulouse, Toulouse

9. Emergency Department, University Hospital of Montpellier, Montpellier

10. Emergency Department, University Hospital of Besancon, Besancon

11. Emergency Department, University Hospital of La Pitié, Paris

12. IMAGEs laboratory ICUBE UMR 7357 CNRS, Illkirch-Graffenstaden

13. Emergency Department, Hospital of Cahors, Cahors

14. Unité INSERM UMR 1260, Regenerative NanoMedicine (RNM), Fédération de Médecine Translationnelle (FMTS), Faculté de Médecine - Université de Strasbourg, Strasbourg Cedex

15. Public Health Department, Hôpitaux Universitaires de Strasbourg, 1 place de l’hôpital, CHRU of Strasbourg Strasbourg

16. ICUBE laboratory UMR 7357 CNRS, IMAGEs group, Illkirch-Graffenstaden, France

Abstract

Background The assessment of acute heart failure (AHF) prognosis is primordial in emergency setting. Although AHF management is exhaustively codified using mortality predictors, there is currently no recommended scoring system for assessing prognosis. The European Society of Cardiology (ESC) recommends a comprehensive assessment of global AHF prognosis, considering in-hospital mortality, early rehospitalization rates and the length of hospital stay. Objective We aimed to prospectively evaluate the performance of the Multiple Estimation of risk based on the Emergency department Spanish Score In patients with AHF (MEESSI-AHF) score in estimating short prognosis according to the ESC guidelines. Design, settings and patients A multicenter study was conducted between November 2020, and June 2021. Adult patients who presented to eleven French hospitals for AHF were prospectively included. Outcome measures and analysis According to MEESSI-AHF score, patients were stratified in four categories corresponding to mortality risk: low-, intermediate-, high- and very high-risk groups. The primary outcome was the number of days alive and out of the hospital during the 30-day period following admission to the Emergency Department (ED). Results In total, 390 patients were included. The number of days alive and out of the hospital decreased significatively with increasing MEESSI-AHF risk groups, ranging from 21.2 days (20.3–22.3 days) for the low-risk, 20 days (19.3–20.5 days) for intermediate risk,18.6 days (17.6–19.6 days) for the high-risk and 17.9 days (16.9–18.9 days) very high-risk category. Conclusion Among patients admitted to ED for an episode of AHF, the MEESSI-AHF score estimates with good performance the number of days alive and out of the hospital.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Emergency Medicine

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