Intraoperative Detection of Malignant Gliomas by 5-Aminolevulinic Acid-induced Porphyrin Fluorescence

Author:

Walter Stummer1,Susanne Stocker2,Simon Wagner2,Herbert Stepp2,Clemens Fritsch3,Claudia Goetz1,Alwin E. Goetz4,Rainer Kiefmann4,Hans J. Reulen1

Affiliation:

1. Department of Neurosurgery Institute for Anaesthesiology

2. Laser Research Laboratory Institute for Anaesthesiology

3. Department of Dermatology Heinrich-Heine-University, Dusseldorf, Germany

4. Klinikum Grojβhadern, Ludwig-Maximilians University, Munich Heinrich-Heine-University, Dusseldorf, Germany

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Clinical Neurology,Surgery

Reference32 articles.

1. Effect of the extent of surgical resection on survival and quality of life in patients with supratentorial glioblastomas and anaplastic astrocytomas;Ammirati;Neurosurgery,1987

2. Porphyrins, porphyrias, cancer and photodynamic therapy: A model of carcinogenesis;Batlle;J Photochem Photobiol B,1993

3. Grading of astrocytomas: A simple and reproducible method;Daumas-Duport;Cancer,1988

4. Resection, biopsy, and survival in malignant glial neoplasms: A retrospective study of clinical parameters, therapy and outcome;Devaux;J Neurosurg,1993

5. Phototoxic damage to sebaceous glands and hair follicles of mice after systemic administration of 5-aminolevulinic acid correlates with localized protoporphyrin IX fluorescence;Divaris;Am J Pathol,1990

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