Update 2011: leflunomide in rheumatoid arthritis – strengths and weaknesses
Author:
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Rheumatology
Reference29 articles.
1. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs;Smolen;Ann Rheum Dis,2010
2. Investigation of the influence of CYP1A2 and CYP2C19 genetic polymorphism on 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide (A771726) pharmacokinetics in leflunomide-treated patients with rheumatoid arthritis;Grabar;Drug Metab Dispos,2009
3. Dihydroorotate dehydrogenase polymorphism influences the toxicity of leflunomide treatment in patients with rheumatoid arthritis;Grabar;Ann Rheum Dis,2009
4. Effect of ABCG2 genotypes on the pharmacokinetics of A771726, an active metabolite of prodrug leflunomide, and association of A771726 exposure with serum uric acid level.;Kim;Eur J Clin Pharmacol,2011
5. Effectiveness of leflunomide in patients with juvenile idiopathic arthritis in clinical practice;Foeldvari;J Rheumatol,2010
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