Herpes simplex encephalitis in a patient abusing morphine: a case report from Nepal-Reference-Cited by-同舟云学术

Herpes simplex encephalitis in a patient abusing morphine: a case report from Nepal

Published:2023-04 Issue:4 Volume:85 Page:1216-1219
ISSN:2049-0801
Container-title:Annals of Medicine & Surgery
language:en
Short-container-title:

Author:

KC Bijay¹,Bhattarai Himal B.²^ORCID,Shah Sangam³,Bhattarai Madhur³,Uprety Manish⁴^ORCID,Jha Abhishek¹,Rayamajhi Sushil⁵^ORCID,Pant Subhash⁶,Limbu Chandra P.²,Shrestha Babu R.¹

Affiliation:

1. Department of Anesthesia and Intensive Care

2. P.T. Birta City Hospital and Research Centre, Birtamod, Jhapa

3. Institute of Medicine, Tribhuvan University, Maharajgunj

4. Kathmandu University School of Medical Science, Dhulikhel Hospital, Panauti

5. Swacon International Hospital, Kathmandu

6. Department of Medicine, Kathmandu Medical College and Teaching Hospital

Abstract

Introduction: Herpes simplex encephalitis results from either primary infection with the herpes simplex virus (HSV) or reactivation of latent HSV residing within the nuclei of sensory neurons. Opioid’s administration is known to reactivate HSV infection. Case presentation: We report a 46-year-old male who was in a rehabilitation center for 17 days for abusing morphine for 2 years. Discussion: Chronic morphine use weakens immune system thereby, making body prone for development of infection. Opioids may reactivate HSV infection because of their immunosuppressive function. Conclusion: Herpes simplex encephalitis is a potentially fatal condition but can be treated with early diagnosis and intervention.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine,Surgery

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